Takeaways from “The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race” by Walter Isaacson

I recently read The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race by Walter Isaacson, the bestselling author of Steve Jobs. The book started at the story of Jennifer Doudna and expanded onto the potential applications of gene editing and what that technology could potentially mean for the human race. I highly recommend the book.

My key take-aways are as follows:


Curiosity-driven motives lead to unusual discoveries

The word “curiosity” appeared more than 30 times in the book. It reminds me of the principle that I always think about, “If you don’t have passion, you cannot win.”

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Re-read “Pioneering Portfolio Management” by David Swensen

I re-read the copy of the book that I bought four years ago, when I was learning about investing at the Yale Endowment. My new takeaways are as follows.


Dare to be great

Human beings are a social species. To survive, we are inclined to huddle together and to imitate each other. For most investors, they care so much about how other people see them that they dare not say anything different or do anything new. If they do, they risk their job security, professional status, and social networks. Those behavioral inclinations are simply a natural part of us, and they are difficult to overcome – just like a software cannot debug itself. Most investors are conventional and do not have the ability to be different. Successful investors are unconventional, and so they are rare.

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My Learnings (2017 to 2021)

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It is a difficult decision for me, but I have determined that now is the time to leave my current position and to pursue a similar but not so similar path, something that is more true to my heart.

Reflecting upon the past four years, I distilled my key learnings into the following.

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A Few Thoughts From 2020

“Culture eats strategy for lunch”

2020 laid bare the truth in that saying. To manage a pandemic, it is not about whether a country has the strategy, the money, or the technology to handle the virus; it is about the culture of its people.

My wife and I were in Beijing during the outbreak. The news broke out during dinner time on January 20, 2020. Within an hour or two of that news, as we left restaurant that night, some people were already wearing masks. By the second day, some 20% to 50% people we saw in Beijing and Shanghai were wearing masks. Mask wearing — it was a culture.

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It’s a volume game

I am always intrigued by the question of “what are your interests?” I ask myself this question often. I also throw this question to others. One business school student answered: “my interest is to find an investment banking job.” Well, he was not really answering my question.

Many people see their short-term goals as their interests. This is a mistake and I believe this is why many high-achieving people don’t feel happy (even after they have attained their goals). By not seeking to know their own interests, people end up spending their entire life doing things they don’t like and they don’t care.

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Scientific Thinking and the Danger of Not Doing So

As I wrote in December 2019, “Think Scientifically” was one of my five key takeaways from 2019. Of late, it has become increasingly obvious to me that there is great value in scientific thinking — and, not doing so is unusually dangerous.

To think scientifically, I believe, is to think independently, to be grounded in facts and free of preconceived notions. Scientific thinking seeks truth, not opinions. It welcomes different ideas, new ideas. It also encompasses the willingness to acknowledge that “I can be wrong.”

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Cultural Differences in the Handling of the Coronavirus

In the evening of January 20, 2020, China’s respiratory expert Zhong Nanshan confirmed and announced to the public that the virus had passed from person-to-person. I was in Beijing that Monday evening.

By 9pm that day, when I looked out onto the street, many citizens already had surgical masks on. By the next day, as I was travelling through China on a high-speed train, somewhere between 20% to 50% of people I saw started wearing masks.

Within three days, on January 23, Wuhan was locked down. In the following few days, Chinese cities started requiring citizens to wear surgical masks and implementing other types of social distancing measures. For example, on January 26, 2020, Suzhou announced that all passengers using the city’s subway system must wear surgical masks.

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Five Takeaways From 2019

This is a year-end personal reflection piece. The following five takeaways of mine are inherently backward-looking, but hopefully by examining the past I become more informed going forward.

#1 Think Independently

We giggle when watching lemmings do all kinds of funny things in a group together. But we are not that different — we humans are just as social species as lemmings are. As a general observation, we like people who are like us — a tendency which builds an intellectual echo chamber that confines and reinforces our thinking, making it less independent.

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